PUBLICATIONS
2025
Molecular Dynamics Study on the Influence of the CLK Motif on the Structural Stability of Collagen-Like Peptides Adsorbed on Gold Nanosurfaces
Constanza Galaz-Araya, Pablo Galaz-Davison, Diego Cortés-Arriagada, Ricardo A. Zamora* and Horacio Poblete*
Unveiling the potential of RADA16-I peptide-coated silver nanoparticles for biomedical uses: a computational study
Matías Zúñiga-Bustos, Constanza Galaz-Araya and Horacio Poblete*
2024
Exploring the photophysics of cinnamoyl-coumarin derivatives in cucurbit [7]uril complexes and assessing phototoxicity in HeLa cells
Daniel Zúñiga-Núñez, Francisco Mura, Nory Mariño-Ocampo, Benjamín Zúñiga, José Robinson-Duggon, Ricardo A. Zamora, Horacio Poblete, Alexis Aspée, Denis Fuentealba
Multipurpose On-the-Spot Peptide-Based Hydrogels for Skin, Cornea, and Heart Repair
Alex Ross, Xixi Guo, German A. Mercado Salazar, Sergio David Garcia Schejtman, Jinane El-Hage, Maxime Comtois-Bona, Aidan Macadam, Irene Guzman-Soto, Hiroki Takaya, Kevin Hu, Bryan Liu, Ryan Tu, Bilal Siddiqi, Erica Anderson, Marcelo Muñoz, Patricio Briones-Rebolledo, Tianqin Ning, May Griffith, Benjamin Rotsein, Horacio Poblete, Jianyu Li, Marc Ruel, Erik J. Suuronen, Emilio I. Alarcon
Charybdotoxin binding to shaker potassium channels, a case of lock and key equilibrium: Voltage, external potassium, and temperature dependence
Nieves Navarro, Francisca Salas, Horacio Poblete, David Naranjo.
Time-resolved fluorescence and anisotropy-sensitive 1,2-dimyristoyl-sn-glycero-3-(7-aminocoumarin) phosphoetanolamide probe for studying membrane lipid domains
Daniel Zúñiga-Núñez, Francisco Mura, Nory Mariño-Ocampo, Patricio Briones-Rebolledo, Horacio Poblete, Jean-Maurice Mallet, Denis Fuentealba, Alexis Aspée.
2023
Thermodynamics of the physisorption of capping agents on silver nanoparticles
Matías Zúñiga-Bustos, Jeffrey Comer and Horacio Poblete
Stabilization of Carbon Nanotubes and Graphene by Tween-80: Mechanistic Insights from Spectroscopic and Simulation Studies
Alpna Bisht, Matías Zuñiga-Bustos, Garima Prasher, Surbhi Gautam, Horacio Poblete, Raman Preet Singh
2022
Nanoengineered Sprayable Therapy for Treating Myocardial Infarction
Marcelo Muñoz, Cagla Eren Cimenci, Keshav Goel, Maxime Comtois-Bona, Mahir Hossain, Christopher McTiernan, Matias Zuñiga-Bustos, Alex Ross, Brenda Truong, Darryl R Davis, Wenbin Liang, Benjamin Rotstein, Marc Ruel, Horacio Poblete, Erik J Suuronen, Emilio I Alarcon
Self-Organization Dynamics of Collagen-like Peptides Crosslinking Is Driven by Rose-Bengal-Mediated Electrostatic Bridges
Roberto Rosales-Rojas, Matías Zuñiga-Bustos, Francisca Salas-Sepúlveda, Constanza Galaz-Araya, Ricardo A Zamora, Horacio Poblete
Structural Insights into the Inhibition Site in the Phosphorylcholine Phosphatase Enzyme of Pseudomonas aeruginosa
Daniel Bustos, Erix W Hernández-Rodríguez, Horacio Poblete, Jans Alzate-Morales, Cecilia Challier, Cristhian Boetsch, Ariela Vergara-Jaque, Paola Beassoni
Molecular rotors as reporters for viscosity of solutions of collagen like peptides
Christopher D McTiernan, Matias Zuñiga-Bustos, Roberto Rosales-Rojas, Pablo Barrias, May Griffith, Horacio Poblete, Peter S Sherin, Ismael López-Duarte, Marina K Kuimova, Emilio I Alarcon
2021
2020
Cinnamoyl–coumarin hybrid derivatives with remarkable fluorescent molecular-rotor properties in mixtures of DPPC: DOPC LUVs
Daniel Zuniga-Nunez, Francisco Mura, Ricardo A Zamora, Horacio Poblete, Denis Fuentealba, Alexis Aspee
KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis
José Rivas, Nicolás Díaz, Ian Silva, Danna Morales, Boris Lavanderos, Alhejandra Álvarez, María Paz Saldías, Eduardo Pulgar, Pablo Cruz, Diego Maureira, Guillermo Flores, Alicia Colombo, Constanza Blanco, Héctor R Contreras, Fabián Jaña, Ivan Gallegos, Miguel L Concha, Ariela Vergara‐Jaque, Horacio Poblete, Wendy González, Diego Varela, James S Trimmer, Mónica Cáceres, Oscar Cerda
2019
Large-scale state-dependent membrane remodeling by a transporter protein
Wenchang Zhou, Giacomo Fiorin, Claudio Anselmi, Hossein Ali Karimi-Varzaneh, Horacio Poblete, Lucy R Forrest, José D Faraldo-Gómez
Light-Activated Peptide-Based Materials for Sutureless Wound Closure
Christopher D McTiernan, David C Cortes, Caitlin Lazurko, Selya Amrani, Roberto Rosales-Rojas, Matias Zuñiga-Bustos, Veronika Sedlakova, Horacio Poblete, Kevin Stamplecoskie, Erik J Suuronen, Emilio I Alarcon
A Structural Model of the Inactivation Gate of Voltage-Activated Potassium Channels
Ariela Vergara-Jaque, Francisco Palma-Cerda, Adam S Lowet, Angel de la Cruz Landrau, Horacio Poblete, Alexander Sukharev, Jeffrey Comer, Miguel Holmgren
Trans-toxin ion-sensitivity of charybdotoxin-blocked potassium-channels reveals unbinding transitional states
Hans Moldenhauer, Ignacio Díaz-Franulic, Horacio Poblete, David Naranjo
Nanoparticle concentration vs surface area in the interaction of thiol-containing molecules: toward a rational nanoarchitectural design of hybrid materials
Keshav Goel, Matias Zuñiga-Bustos, Caitlin Lazurko, Erik Jacques, Constanza Galaz-Araya, Francisco Valenzuela-Henriquez, Natalia L Pacioni, Jean-François Couture, Horacio Poblete, Emilio I Alarcon
Computational Methodologies for Exploring Nano-engineered Materials
Ariela Vergara-Jaque, Matías Zúñiga, Horacio Poblete
Experimental and Computational Characterization of the Interaction between Gold Nanoparticles and Polyamidoamine Dendrimers
María Belén Camarada, J Comer, H Poblete, ER Azhagiya Singam, V Marquez-Miranda, C Morales-Verdejo, FD Gonzalez-Nilo
Thermodynamics of adsorption on graphenic surfaces from aqueous solution
ER Azhagiya Singam, Yuntao Zhang, Geraldine Magnin, Ingrid Miranda-Carvajal, Logan Coates, Ravindra Thakkar, Horacio Poblete, Jeffrey Comer
2018
Computational modeling of the adsorption of capping agent biomolecules to inorganic nanoparticles
Horacio Poblete, Jeffrey Comer
Computational Methodologies for Exploring Nano-engineered Materials
Ariela Vergara-Jaque, Matías Zúñiga, Horacio Poblete
Theoretical rationalisation of the photophysics of a TICT excited state of cinnamoyl–coumarin derivatives in homogeneous and biological membrane models
Daniel Zuniga-Nunez, Ricardo A Zamora, Pablo Barrias, Cristian Tirapegui, Horacio Poblete, Gloria Cardenas-Jiron, Emilio I Alarcon, Alexis Aspee
Effect of nanosilver surfaces on peptide reactivity towards reactive oxygen species
Erik Jacques, Manuel Ahumada, Brianna Rector, Goonay Yousefalizadeh, Constanza Galaz-Araya, Rodrigo Recabarren, Kevin Stamplecoskie, Horacio Poblete, Emilio I Alarcon
2017
Rose Bengal binding to collagen and tissue photobonding
Emilio I Alarcon, Horacio Poblete, HeeGwang Roh, Jean-Francois Couture, Jeffrey Comer, Irene E Kochevar
Determinants of Alanine Dipeptide Conformational Equilibria on Graphene and Hydroxylated Derivatives
Horacio Poblete, Ingrid Miranda-Carvajal, Jeffrey Comer
A Structural Model of the Inactivation Gate of Voltage Activated Potassium Channels
Ariela Vergara-Jaque, Francisco Palma-Cerda, Horacio Poblete, Adam Lowet, Alexander Sukharev, Jeffrey Comer, Miguel Holmgren
Insights into the Gating Mechanism of Excitatory Amino Acid Transporters-Associated Anion Channel
Delany Torres-Salazar, Horacio Poblete, Aneysis Gonzalez-Suarez, Ariela Vergara-Jaque, Jennie Garcia-Olivares, Jeffrey Comer, Susan G Amara
Membrane Remodeling by GltPh in the Inward- and Outward-Facing Conformations Explains Lack of Protomer Cooperativity
Wenchang Zhou, Claudio Anselmi, Horacio Poblete, Ali Karimi, Lucy Forrest, Jose Faraldo-Gomez
Novel specific peptides as superior surface stabilizers for silver nano structures: role of peptide chain length
M Ahumada, E Jacques, C Andronic, J Comer, H Poblete, EI Alarcon
2016
The dynamic nonprime binding of sampatrilat to the C-domain of angiotensin-converting enzyme
Rajni K Sharma, Marlene Espinoza-Moraga, Horacio Poblete, Ross G Douglas, Edward D Sturrock, Julio Caballero, Kelly Chibale
Allosterism and Structure in Thermally Activated Transient Receptor Potential Channels
Ignacio Diaz-Franulic, Horacio Poblete, Germán Miño-Galaz, Carlos González, Ramón Latorre
Elucidating the Anion Channel Gating Mechanism in Excitatory Amino Acid Transporters
Delany Torres Salazar, Horacio Poblete, Aneysis Gonzalez, Ariela Vergara-Jaque, Jeffrey Comer, Susan G Amara
Allosterism and Structure in Thermally Activated Transient Receptor Potential Channels
Ignacio Diaz-Franulic, Horacio Poblete, Germán Miño-Galaz, Carlos González, Ramón Latorre
The dynamic nonprime binding of sampatrilat to the C-domain of angiotensin-converting enzyme
Rajni K Sharma, Marlene Espinoza-Moraga, Horacio Poblete, Ross G Douglas, Edward D Sturrock, Julio Caballero, Kelly Chibale
Perspectives of TRPV1 Function on the Neurogenesis and Neural Plasticity
R Ramírez-Barrantes, C Cordova, H Poblete, P Muñoz, I Marchant, F Wianny, P Olivero
2015
New insights into peptide–silver nanoparticle interaction: Deciphering the role of cysteine and lysine in the peptide sequence
Horacio Poblete, Anirudh Agarwal, Suma S Thomas, Cornelia Bohne, Ranjithkumar Ravichandran, Jaywant Phopase, Jeffrey Comer, Emilio I Alarcon
Predicting adsorption affinities of small molecules on carbon nanotubes using molecular dynamics simulation
Jeffrey Comer, Ran Chen, Horacio Poblete, Ariela Vergara-Jaque, Jim E Riviere
Molecular determinants of phosphatidylinositol 4, 5-bisphosphate (PI (4, 5) P2) binding to transient receptor potential V1 (TRPV1) channels
Horacio Poblete, Ingrid Oyarzún, Pablo Olivero, Jeffrey Comer, Matías Zuñiga, Romina V Sepulveda, David Báez-Nieto, Carlos González Leon, Fernando González-Nilo, Ramón Latorre
Study of the affinity between the protein kinase PKA and peptide substrates derived from kemptide using molecular dynamics simulations and MM/GBSA
Karel Mena-Ulecia, Ariela Vergara-Jaque, Horacio Poblete, William Tiznado, Julio Caballero
2014
2013
Impact of dye‐protein interaction and silver nanoparticles on rose Bengal photophysical behavior and protein photocrosslinking
Madeline J Simpson, Horacio Poblete, May Griffith, Emilio I Alarcon, Juan C Scaiano
Association of nicotinic acid with a poly (amidoamine) dendrimer studied by molecular dynamics simulations
Julio Caballero, Horacio Poblete, Cristell Navarro, Jans H Alzate-Morales
Human serum albumin as protecting agent of silver nanoparticles: role of the protein conformation and amine groups in the nanoparticle stabilization
Emilio I Alarcon, Carlos J Bueno-Alejo, Christopher W Noel, Kevin G Stamplecoskie, Natalia L Pacioni, Horacio Poblete, Juan Cesar Scaiano
Molecular basis of drug resistance in A/H1N1 virus
Ariela Vergara-Jaque, Horacio Poblete, Eric H Lee, Klaus Schulten, Fernando González-Nilo, Christophe Chipot
2012
2010
Stereoselective interaction of epimeric naproxen-RGD peptides with human serum albumin
Maria Gonzalez-Bejar, Emilio Alarcon, Horacio Poblete, Juan C Scaiano, Julia Perez-Prieto
Photophysics and photochemistry of dyes bound to human serum albumin are determined by the dye localization
Emilio Isaac Alarcón Abarzúa, Alexis Aspee, Faustino Eduardo Moran Vieyra, Claudio D Borsarelli, Eduardo A Lissi, Fernando Danilo González Nilo, Horacio Poblete, JC Scaiano
2009
Antioxidant reactivity toward nitroxide probes anchored into human serum albumin. A new model for studying antioxidant repairing capacity of protein radicals
Alexis Aspée, Alejandra Orrego, Emilio Alarcón, Camilo López-Alarcón, Horacio Poblete, Danilo González-Nilo
